Lycopene Ameliorates Liver Inflammation and Redox Status in Mice Exposed to Long-Term Cigarette Smoke

Table 2

The semiquantitative score values (minimum-maximum) of the histological lesions found in the liver.

Lesions	CG	OG	CSG	L25CSG	L50CSG
Hydropic degeneration	2 (1-3)	2 (1-3)	2 (1-3)	1 (1-2)	1 (1-3)
Sinusoidal congestion/hyperemia	0 (0-1)	0 (0-1)	3 (2-3)^a,b	1 (0-1)	1 (0-1)^c
Inflammatory reaction	0 (0)	0 (0-1)	2 (1-3)^a,b	1 (0-1)	0 (0-1)^c
Granulomas	0 (0)	0 (0)	1 (0-1)^a,b	0 (0)^c	0 (0)^c
Bleeding focus	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
Necrosis	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)

CG: control group; OG: oil group; CSG: cigarette smoke group; L25CSG: lycopene 25 mg/kg/day and cigarette smoke group; L50CSG: lycopene 50 mg/kg/day and cigarette smoke group. a represents a significant difference between CSG when compared to CG; b represents a significant difference between CSG when compared to OG; c represents a significant difference when compared to CSG. The data were analyzed by Kruskal-Wallis followed by Dunn’s posttest, animals per group ().