Exosomes Derived from M2 Macrophages Exert a Therapeutic Effect via Inhibition of the PI3K/AKT/mTOR Pathway in Rats with Knee Osteoarthritic

Figure 6

Schematic diagram of the protective mechanism of exosomes derived from M2 macrophage against KOA through the PI3K/AKT/mTOR signaling pathway. Exosomes derived from M2 macrophage can regulate the production of proinflammatory factors and the level of osteogenesis-related proteins.