Research Article

UPLC-ESI-MS/MS Analysis and Evaluation of Antioxidant Activity of Total Flavonoid Extract from Paeonia lactiflora Seed Peel and Optimization by Response Surface Methodology (RSM)

Table 2

Analysis of variance for the response surface model for the flavonoid yield of P. lactiflora seed peel.

SourceSum of squaresDfMean square value value

Model9.6691.0782.17<0.0001
0.3410.3425.870.0014
0.8710.8766.25<0.0001
10.0760.7910
0.06510.0654.980.0609
0.07710.0775.870.0458
10.700.4310
1.2811.2897.94<0.0001
2.8312.83217.00<0.0001
3.3613.36257.04<0.0001
Residual0.09170.013
Lack of fit0.06330.0212.960.1611
Pure error0.0284
Cor total9.7516
0.9906
Adj 0.9786
Pred 0.8920
Adeq precision23.971

: ethanol concentration; : liquid-solid ratio; : ultrasonic time.