Overview of Candida albicans and Human Papillomavirus (HPV) Infection Agents and their Biomolecular Mechanisms in Promoting Oral Cancer in Pediatric Patients

Table 1

There are over 450 types of HPV. The HPV’s genotypes are divided into 4 groups according to the associate oncogenic risk by IARC/WHO (source from https://monographs.iarc.who.int/agents-classified-by-the-iarc/).

Group	HPV virus
1	Carcinogenic to humans: human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59 (the HPV types that have been classified as carcinogenic to humans can differ by an order of magnitude in risk for cervical cancer)
2A	Probably carcinogenic to humans: human papillomavirus type 68
2B	Possibly carcinogenic to humans: human papillomavirus types 26, 53, 66, 67, 70, 73, and 82; human papillomavirus types 30, 34, 69, 85, and 97 (classified by phylogenetic analogy to the HPV genus alpha types classified in group 1); human papillomavirus types 5 and 8 (in patients with epidermodysplasia verruciformis)
3	Not classifiable as to its carcinogenicity to humans: human papillomavirus genus beta (except types 5 and 8) and genus gamma; human papillomavirus types 6 and 11