Expression of Circulating MicroRNAs and Myokines and Interactions with Serum Osteopontin in Type 2 Diabetic Patients with Moderate and Poor Glycemic Control: A Biochemical and Molecular Study

Figure 1

Gender differences in fold changes of proinflammatory cytokines (CRP, TNF-α, IL-6, IL-8, IL-18, and IL-1β) in moderate glycemic controlled T2D (MCT2D; >7-8% HbA1c, ) (a) and poor glycemic controlled T2D (PCT2D; >8% HbA1c, ) (b). Females of controlled and poor type 2 diabetic groups showed significant increase in all studied cytokines compared to males of the same group. Significance based on gender difference (male vs. female) at ^a and ^b.

(a)

(b)