Retinal Degeneration in a Murine Model of Retinal Ischemia by Unilateral Common Carotid Artery Occlusion

Figure 4

Retinal dysfunction 4 weeks after UCCAO. (a) Representative waveforms of scotopic a-wave, b-wave, and oscillatory potentials (OP1-4) responsive to a stimulus intensity of 10 cd.s/m² 4 weeks after UCCAO. (b) The amplitudes of scotopic OPs in the UCCAO-operated eyes significantly decreased compared to those in the sham-operated eyes ( per group). and . (c, d) The amplitude of scotopic b-wave (not scotopic a-wave) in the UCCAO-operated eyes significantly decreased compared to that in the sham-operated eyes (0.5 and 10 cd.s/m²) ( per group). . (e) Representative waveforms of photopic b-wave responsive to a stimulus intensity of 20 cd.s/m² 4 weeks after UCCAO. (f) The amplitude of photopic b-wave in the UCCAO-operated eyes decreased compared to that in the sham-operated eyes (4 and 20 cd.s/m²) ( per group). and . (g) The relative ratio of b/a-wave was calculated using the values in Figures 3(c) and 3(d) and (c, d) (10 cd.s/m²). . The data were analyzed using Student’s -test (two-tailed) and presented as .

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