Identification of Hypoxia-Related Differentially Expressed Genes and Construction of the Clinical Prognostic Predictor in Hepatocellular Carcinoma by Bioinformatic Analysis

Figure 5

Hypoxia-related prognostic predictor (PP) of hepatocellular carcinoma patients. (a) High- and low-risk group with the median risk score as the cut-off point according to the risk score formula. Red indicates high risk and green low risk. (b) Kaplan-Meier plot represents that patients in the high-risk group had significantly shorter overall survival time than those in the low-risk group. (c) The overall survival of patients in the high- and low-risk group. The dotted line was the dividing line between high- and low-risk group of HCC patients. The right side of the dotted line represented the high-risk group, the left side represented the low-risk group, the red dots represented patients who had died, and the green dots represented patients who had still survived (d) The heat map shows the distribution of these 12 key gene expression profiles in the TCGA dataset.

(a)

(b)

(c)

(d)