MAPK and Notch-Mediated Effects of Meso-Xanthin F199 Compounds on Proliferative Activity and Apoptosis of Human Melanocytes in Three-Dimensional Culture

Figure 3

Heatmap of semiquantitative protein distribution in the shared proteome for M2319, Nm01, and Am02 melanocytes. The sample M2319 was employed as a baseline for normalization. Range correlation of proteins was performed using Spearman’s test. The total size of the tested proteome involved 434 protein identifications. Samples Nm01 and Am02 are at the closest localization according to the results of cluster analysis, while M2319 is the most distal.