Research Article

Quantification of Biventricular Myocardial Strain Using CMR Feature Tracking: Reproducibility in Small Animals

Table 2

Intraobserver, interobserver, and interstudy reproducibilities for global LV and RV strain assessment.

ParameterS1 (%)S2 (%)Mean differenceLimits of agreementICC (95% CI)Coefficient of variations

IntraobserverLLSLAX-0.19-1.58 to 1.210.99 (0.96 to 1.00)3.36%
LCSSAX-0.05-2.56 to 2.460.94 (0.81 to 0.98)4.10%
LRSSAX1.43-4.50 to 7.360.84 (0.54 to 0.95)7.06%
RLSLAX-0.58-3.17 to 2.020.97 (0.89 to 0.99)3.92%
RCSSAX-1.64-4.06 to 0.790.78 (0.02 to 0.95)7.22%
InterobserverLLSLAX-0.20-1.98 to 1.580.98 (0.93 to 0.99)3.51%
LCSSAX0.91-2.56 to 4.380.86 (0.58 to 0.96)6.74%
LRSSAX0.37-7.61 to 8.360.76 (0.36 to 0.93)8.58%
RLSLAX-2.4-7.57 to 2.790.84 (0.30 to 0.96)11.41%
RCSSAX-1.68-6.09 to 2.730.65 (0.11 to 0.89)9.98%
InterstudyLLSLAX-0.44-4.26 to 3.370.90 (0.71 to 0.97)8.81%
LCSSAX-0.33-6.11 to 5.440.77 (0.38 to 0.93)11.11%
LRSSAX-0.57-15.07 to 13.920.50 (0.10 to 0.83)18.06%
RLSLAX-2.14-10.09 to 5.810.70 (0.26 to 0.90)11.99%
RCSSAX-1.88-8.29 to 4.520.36 (0.14 to 0.74)12.88%

Results are shown as the . S1 and S2 refer to the two readings among intraobserver, interobserver, and interstudy reproducibilities. LLSLAX: left ventricular long-axis longitudinal strain; LRSLAX: left ventricular long-axis radial strain; LCSSAX: left ventricular short-axis circumferential strain; LRSSAX: left ventricular short-axis radial strain; RLSLAX: right ventricular long-axis longitudinal strain; RCSSAX: right ventricular short-axis circumferential strain; ICC: intraclass correlation coefficient; CI: confidence interval.