Research Article

Quantification of Biventricular Myocardial Strain Using CMR Feature Tracking: Reproducibility in Small Animals

Table 3

Intraobserver, interobserver, and interstudy reproducibilities for segmental LV and RV strain assessment.

ParameterMean differenceLimits of agreementICC (95% CI)Coefficient of variations

IntraobserverLLSLAX-0.16-9.16 to 8.830.94 (0.92 to 0.96)7.41%
LCSSAX-0.21-5.98 to 5.570.95 (0.94 to 0.96)14.5%
LRSSAX1.08-9.46 to 11.620.95 (0.93 to 0.96)7.6%
RLSLAX-0.01-11.96 to 11.990.94 (0.91 to 0.96)5.79%
RCSSAX-1.51-9.42 to 6.390.78 (0.67 to 0.85)10.11%
InterobserverLLSLAX-0.19-10.06 to 9.680.93 (0.90 to 0.96)19.81%
LCSSAX1.11-16.42 to 18.640.54 (0.43 to 0.63)37.4%
LRSSAX-2.03-28.66 to 24.600.64 (0.55 to 0.72)42.6%
RLSLAX-1.74-13.61 to 10.140.95 (0.92 to 0.97)19.5%
RCSSAX-1.13-14.57 to 12.310.47 (0.27 to 0.63)18.35%
InterstudyLLSLAX-0.05-16.04 to 15.940.80 (0.71 to 0.87)21.74%
LCSSAX-0.52-8.79 to 7.760.91 (0.88 to 0.93)4.4%
LRSSAX0.18-18.44 to 18.790.84 (0.79 to 0.88)58.3%
RLSLAX-0.79-21.56 to 19.980.80 (0.69 to 0.87)6.5%
RCSSAX-2.58-14.35 to 9.190.54 (0.36 to 0.69)15.29%

Results are shown as the . S1 and S2 refer to the two readings among intraobserver, interobserver, and interstudy reproducibilities. LLSLAX: left ventricular long-axis longitudinal strain; LRSLAX: left ventricular long-axis radial strain; LCSSAX: left ventricular short-axis circumferential strain; LRSSAX: left ventricular short-axis radial strain; RLSLAX: right ventricular long-axis longitudinal strain; RCSSAX: right ventricular short-axis circumferential strain; ICC: intraclass correlation coefficient; CI: confidence interval.