SIRT1 Inhibits Apoptosis by Promoting Autophagic Flux in Human Nucleus Pulposus Cells in the Key Stage of Degeneration via ERK Signal Pathway

<div>Schematic representation of the proposed mechanism by which SIRT1 inhibits apoptosis by promoting autophagic flux through the ERK, but not AKT, pathway in mildly degenerative human intervertebral disc NP cells.</div>

BioMed Research International

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Figure 6

Figure 6: SIRT1 Inhibits Apoptosis by Promoting Autophagic Flux in Human Nucleus Pulposus Cells in the Key Stage of Degeneration via ERK Signal Pathway 

Figure 6 | SIRT1 Inhibits Apoptosis by Promoting Autophagic Flux in Human Nucleus Pulposus Cells in the Key Stage of Degeneration via ERK Signal Pathway 