Research Article
Both Chloroquine and Lopinavir/Ritonavir Are Ineffective for COVID-19 Treatment and Combined Worsen the Pathology: A Single-Center Experience with Severely Ill Patients
Figure 5
Modulation of pathology biomarkers. The CALL score was calculated for each patient in each group (a), and the concentration of C-reactive protein (CRP) (b), d-Dimer (c), lactate dehydrogenase (LDH) (d), and ferritin (e) was plotted into a histogram for each patient from day 1 to day 7. A Student’s tests (a) and ANOVA tests (b–e) were performed comparing each treatment against ST, a was considered significant. L/R: lopinavir/ritonavir; Chlo: chloroquine; L/R+Chlo: lopinavir/ritonavir plus chloroquine; ST: standard treatment.
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