Using Elevated Cholesterol Synthesis as a Prognostic Marker in Wilms’ Tumor: A Bioinformatic Analysis

Figure 1

Wilms tumor samples with higher activity of cholesterol synthesis are characterized with worse overall survival. (a) Patients with Wilms tumor were divided into two groups (Chole_high and Chole_low) based on the cholesterol synthesis score. (b) The distribution of the survival status of patients with Wilms tumor along with increased Chole_score. (c) Survival analysis showed that Wilms tumors with decreased Chole_score were featured with prolonged survival time. (d) Cumulative hazard analysis showed that Wilms tumors with increased Chole_score were featured with expanded risk for worse survival.

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