Identification of Potential Gene and MicroRNA Biomarkers of Acute Kidney Injury

Figure 5

PPI network of the overlapping DEGs in miRNA-mRNA networks. (a) PPI network of the CIS group. (b) Subnetwork of the overlapping DEGs of the CIS group. (c) PPI network of the IRI group. (d) Subnetwork of the overlapping DEGs of the IRI group. Red circles, upregulated genes; blue circles, downregulated genes. (e) PPI network of the CIS_IRI group. (f) Subnetwork of the overlapping DEGs in the CIS_IRI group. The overlapping DEGs showed the opposite trend of expression in the CIS and IRI groups. Since the expression trend of overlapping DEGs is not consistent in CIS and IRI, the color of the DEGs is random.

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