An Interpretable Model-Based Prediction of Severity and Crucial Factors in Patients with COVID-19

Table 1

Demographic, clinical characteristics, and laboratory tests of the patients.

	Mild group ()	Severe group ()
Age (years)
Mean (SD)			<0.001
Range	17-81	28-86
Median age	46	64.50
Gender			0.513
Male	67 (41.36%)	13 (36.11%)
Female	95 (58.64%)	23 (63.89%)
Signs and symptoms at admission
Days from onset (days)			0.038
Temperature (°C)			<0.001
Fever	119 (73.46%)	27 (75.00%)	<0.001
Cough	96 (59.29%)	23 (63.89%)	<0.001
Fatigue	34 (20.99%)	10 (27.78%)	0.352
Shortness of breath	16 (9.88%)	7 (19.44%)	0.140
Chest tightness	13 (8.02%)	3 (8.33%)	1
Dyspnea	6 (3.70%)	7 (19.44%)	0.002
Fear of cold	6 (3.70%)	5 (13.89%)	0.026
Diarrhea	8 (4.94%)	1 (2.78%)	1
Headache	8 (4.94%)	1 (2.78%)	1
Dizziness	4 (2.47%)	3 (8.33%)	0.105
Palpitation	1 (0.62%)	3 (8.33%)	0.018
Preexisting disease
Hypertension	11 (6.79%)	8 (22.22%)	0.008
Diabetes	6 (3.70%)	4 (11.11%)	0.077
CAD	5 (3.09%)	2 (5.56%)	0.356
Lung cancer	0	1 (2.78%)	0.176
Myocardial infarction	0	1 (2.78%)	0.176
Cerebral infarction	0	1 (2.78%)	0.176
Tuberculosis	0	1 (2.78%)	0.176
Laboratory tests
WBC (×10^9/L)			0.014
Neutrophil (×10^9/L)			0.001
Neutrophil ratio (%)			<0.001
Lymphocyte (×10^9/L)			<0.001
Lymphocyte ratio (%)			<0.001
NLR			0.004

CAD: coronary artery disease; WBC: white blood cell; NLR: neutrophil-to-lymphocyte ratio. Fisher’s exact test.