Clinical Efficacy of Prodom-Assisted Urokinase in the Treatment of Male Infertility Caused by Impaired Semen Liquefaction

Table 2

Pregnancy rate/time to conception/treatment cost between groups were compared in the first stage.

Groups	PAUT group (n=91)	SAUT group (n=86)	TT group (n=84)	Total (n=261)	x^2/F	P value
Parameters
Pregnancy rate, %	69.23 (63/91)	29.07 (25/86)	22.62 (19/84)	41.00 (107/261)	256.075	<0.0001
Time to conception (months)	1.44±2.66	3.69±2.61	3.86±3.00	3.02±2.96	20.411	<0.0001^†
Treatment cost ($)	658.18±398.40	666.67±507.50	680.56±480.94	692.56±416.03	0.333	0.717^†

Abbreviations: PAUT: prodom-assisted urokinase treatment; SAUT: syringe-assisted urokinase treatment; TT: traditional treatment. P values were calculated using chi-squared and ^†one-way analysis of variance (one-way ANOVA). In the first stage of treatment, the three treatment methods were not the same in terms of the influence of pregnancy rate (χ²=256.075 and ) and time to conception (F=20.411 and ), and the difference in treatment cost (F=0.333 and ) was not significant. Among them, the effect of PAUT on pregnancy rate and time to conception was different from that of SAUT and TT (all ). It can be considered that the PAUT is superior to the SAUT and the TT in increasing the pregnancy rate and shortening the time to conception. The boldface represents statistical significance.