Research Article
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2
Figure 1
Tet ameliorates the miR-202-5p/TRPV2 axis in H/R H9C2 cells. (a) RT-qPCR detecting the expression of miR-202-5p in H/R H9C2 cells treated with Tet and/or miR-202-5p inhibitor. (b) The transfection of miR-202-5p inhibitor was evaluated in H9C2 cells by RT-qPCR. (c, d) Western blot showing the protein expression of TRPV2 in H9C2 cells transfected with miR-202-5p inhibitor. (e) RT-qPCR detecting the mRNA expression of TRPV2 in H/R H9C2 cells treated with Tet and/or miR-202-5p inhibitor. (f–k) Western blot showing the protein expression of TRPV2, pro-caspase3, cleaved caspase3, Bax, and Bcl-2 in H/R H9C2 cells treated with Tet and/or miR-202-5p inhibitor. ns: not significant; ; ; .
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