Impact of Anesthetic Agents on Endothelial Glycocalyx Injury during Total Knee Arthroplasty: Desflurane- vs. Propofol-Based Anesthesia—A Prospective Randomized Controlled Trial

Table 2

Changes of creatinine (Cr), creatinine phosphokinase (CPK), and lactate dehydrogenase (LDH).

		Desflurane group ()	Propofol group ()
Cr (mg/dl)
	Preop	0.8 (0.6-0.9)	0.7 (0.6-0.8)	0.095
	Post 6 h	0.7 (0.6-0.9)	0.7 (0.6-0.8)	0.378
	Post 24 h	0.7 (0.6-0.8)	0.6 (0.6-0.8)	0.266
CPK (U/l)
	Preop	95.0 (79.0-104.0)	59.5 (52.5-112.0)	0.149
	Post 6 h	130.0 (112.0-150.5)	128.5 (116.0-149.5)	0.969
	Post 24 h	215.0 (160.0-248.5)	215.0 (172.0-225.0)	0.836
LDH (IU/l)
	Preop	477.0 (438.5-530.0)	487.0 (426.5-610.0)	0.912
	Post 6 h	544.0 (455.5-645.0)	543.0 (494.0-606.5)	0.954
	Post 24 h	440.0 (377.5-470.0)	477.5 (335.0-568.0)	0.368

Data are expressed as median (interquartile ranges). Cr: serum creatinine; CPK: creatinine phosphokinase; LDH: lactate dehydrogenase; Preop: before anesthesia induction; Post 6 h: at 6 h after discharge from postanesthesia care unit; Post 24 h: at 24 h after discharge from postanesthesia care unit.