Research Article
Anti-Inflammatory Effects of Melatonin and 5-Methoxytryptophol on Lipopolysaccharide-Induced Acute Pulpitis in Rats
Table 2
Histomorphologic scores per group (%).
| Parameters | Scores | Control () | AP () | AP+melatonin () | AP+5-MTX () |
| Locations of the inflammatory reaction | 1 | 100 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 12.5 | 0 | 4 | 0 | 0 | 37.5 | 50 | 5 | 0 | 87.5 | 50 | 50 | 6 | 0 | 12.5 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 0 | Intensity of the inflammatory infiltrate | 1 | 100 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 12.5 | 3 | 0 | 0 | 50 | 50 | 4 | 0 | 100 | 50 | 37.5 | Inflammatory edema | 1 | 100 | 0 | 0 | 0 | 2 | 0 | 100 | 100 | 100 | Extension of pulp necrosis (45 to 105 degrees area) | 1 | 100 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 0 | 62.5 | 75 | 87.5 | 4 | 0 | 37.5 | 25 | 12.5 |
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