A New Mathematical Model for Controlling Tumor Growth Based on Microenvironment Acidity and Oxygen Concentration

Table 3

Summary of time-dependent functions and input parameters for the proposed model.

Parameter	Brief description	Parameter	Brief description
	Probability of PC division in the site () at iteration m		Proliferative rim thickness (determines growth fraction)
	Average overall tumor radius at iteration m		The average radius of the necrotic zone at iteration
	Necrotic fraction		Growth fraction
	The production probability of a nonmutant PC from the mitosis of a mutant PC