Dilation of Brain Veins and Perivascular Infiltration by Glioblastoma Cells in an In Vivo Assay of Early Tumor Angiogenesis

Figure 1

Microphotographs and computed image analysis of the CW performed before and 1 to 3 weeks after U87MG cell grafting. The first vascular change was hypertrophy of the venous-venous anastomoses due to opening of preexisting vessels. At 3 weeks after grafting, arterialized veins (purple) appeared on the cortical surface. Scale bar, 1 mm.