Inhibitory Effect of Multimodal Nanoassemblies against Glycative and Oxidative Stress in Cancer and Glycation Animal Models

Table 2

Stepwise method for the inhibitory effect of nanoassemblies in the lung cancer animal model.

Step	Experiment (dosing) (50 days)	Group 1 ()	Group 2 ()	Group 3 ()	Group 4 ()
Step 1 (acclimatization for one week)	Diet and normal water	Pellet diet/water	Pellet diet/water	Pellet diet/water	Pellet diet/water
Step 2	NDEA	No NDEA	100 ppm of NDEA in drinking water for initial 15 days	100 ppm of NDEA in drinking water for initial 15 days	100 ppm of NDEA in drinking water for initial 15 days
Step 3	500 ppm of PB	No PB	100 ppm of NDEA in drinking water along with 500 ppm PB for remaining 35 days	100 ppm of NDEA in drinking water along with 500 ppm PB for remaining 35 days	100 ppm of NDEA in drinking water along with 500 ppm PB for remaining 35 days
Step 4	Nanoassembly treatment	No treatment	No treatment	1 μM (3mice) and 3 μM (3 mice) of PFT-HSA-TFT-Cy7	1 μM (3 mice) and 3 μM (3 mice) of PFT-Hcy-HSA-Cy7