Epidemiology of Drug- and Herb-Induced Liver Injury Assessed for Causality Using the Updated RUCAM in Two Hospitals from China

Table 2

The relationship between the types of DILI and HILI and causal agents.

Types	Hepatocellular	Cholestatic	Mixed
HILI	26 (3.5)	2 (-3.4)	2 (-0.5)	14.875	0.001
DILI	25 (-3.5)	22 (3.4)	5 (0.5)
Most common agents implicated of DILI (Top3)
Antitumor	7 (-0.8)	11 (2.0)	0 (-2.0)	9.094	0.031
Antimicrobial	7 (1.5)	3 (-1.5)	1 (0.0)
Analgesic-antipyretic	1 (-0.9)	1 (-0.9)	2 (3.0)

Adjusted residuals appear in parentheses below observed frequencies.