Hepatoprotective Screening of Seriphidium kurramense (Qazilb.) Y.R. Ling
Table 4
Effects of SKM on the genotoxic parameters in CCl4-treated rats.
Treatment
Comet length (μm)
Head length (μm)
Tail length (μm)
% DNA in the head
% DNA in the tail
Tail moment (μm)
Control (normal)
d
a
d
a
d
c
DMSO+olive oil
d
a
d
a
d
c
CCl4 (1 mL/kg)
a
c
a
d
a
a
CCl4+silymarin
c
b
c
b
c
c
CCl4+SKM (150 mg/mg)
b
c
b
c
b
b
CCl4+SKM (300 mg/kg)
c
c
b
b
c
c
SKM (150 mg/kg)
d
a
d
a
d
c
SKM (300 mg/kg)
d
a
d
a
d
c
SKM: Seriphidium kurramense methanol extract. Values expressed as (7). Means with different alphabet letters within the column indicate a significant difference ().
