Relationship of PD-1 (PDCD1) and PD-L1 (CD274) Single Nucleotide Polymorphisms with Polycystic Ovary Syndrome

Table 3

H-WE equilibrium test of genotype distribution of SNP loci in PD-1 and PD-L1 genes.

Gene	TagSNP	PCOS		Control
		PD-L1 gene	rs6415794	0.95	0.33	3.18	0.07
rs822339	1.50		0.22	1.36	0.24
rs17804441	1.53		0.22	0.19	0.66
rs2282055	1.59		0.21	0.18	0.67
rs4143815	1.30		0.26	1.41	0.24
rs2890658	3.54		0.06	1.69	0.20
rs2297137	0.15		0.70	2.44	0.12
rs10125854	0.00		0.98	0.95	0.33
rs6476976	1.53		0.22	3.20	0.07
rs702275	2.57		0.11	1.41	0.24
rs16923173	2.93		0.09	3.33	0.07
rs4742095	0.61		0.43	2.97	0.09
PD-1 gene	rs7421861	0.52	0.48	2.97	0.09
	rs2227982	0.14	0.71	1.28	0.26
	rs10204525	0.25	0.62	1.80	0.18

Note: PCOS: polycystic ovary syndrome; SNP: single nucleotide polymorphism. is considered as good agreement with H-WE equilibrium test.