Research Article
Relationship of PD-1 (PDCD1) and PD-L1 (CD274) Single Nucleotide Polymorphisms with Polycystic Ovary Syndrome
Table 6
Haplotype frequency distribution of rs2282055, rs2890658, rs702275, and rs10125854 loci of the PD-L1 gene.
| | Haplotype | Control (frequency) | PCOS (frequency) | | | OR (95% CI) |
| | GAAA | 123.87 (0.18) | 44.38 (0.07) | 35.22 | <0.01 | 0.35 (0.24~0.50) | | TAAA | 38.56 (0.06) | 127.81 (0.19) | 64.70 | <0.01 | 4.35 (2.96~6.31) | | GAAC | 27.11 (0.04) | 59.06 (0.09) | 16.10 | <0.01 | 2.54 (1.59~4.06) | | TAAC | 49.51 (0.07) | 10.86 (0.02) | 22.53 | <0.01 | 0.23 (0.12~0.44) | | GAGC | 18.26 (0.03) | 38.30 (0.06) | 9.51 | <0.01 | 2.39 (1.35~4.22) | | GCAA | 62.45 (0.09) | 93.08 (0.14) | 10.53 | <0.01 | 1.75 (1.24~2.46) | | TCAA | 116.08 (0.17) | 48.16 (0.07) | 25.41 | <0.01 | 0.41 (0.29~0.59) | | GCGA | 51.56 (0.07) | 15.32 (0.02) | 17.44 | <0.01 | 0.31 (0.17~0.55) | | TCGA | 28.12 (0.04) | 86.84 (0.13) | 39.08 | <0.01 | 3.78 (2.43~5.88) | | GCAC | 29.03 (0.04) | 7.74 (0.01) | 10.83 | <0.01 | 0.28 (0.13~0.63) | | TCAC | 24.73 (0.03) | 14.56 (0.02) | 1.59 | 0.21 | | | TCGC | 121.82 (0.17) | 0.41 (0.00) | 121.81 | <0.01 | 0.00 (0.00~0.02) |
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Note: PCOS: polycystic ovary syndrome. . |
