Research Article
Differential Effect of Antioxidants Glutathione and Vitamin C on the Hepatic Injuries Induced by Plasmodium berghei ANKA Infection
Table 1
Histopathological grading of liver lesions at 10 days post-Plasmodium berghei ANKA infection.
| Histological changes | Histopathologic grading | Control | Glutathione (8 mg/kg) | Vitamin C (8 mg/kg) | PbA | PbA+glutathione (8 mg/kg) | PbA+vitamin C (8 mg/kg) |
| Fatty change | 1 | 1 | 0 | 0 | 0 | 0 | Kupffer cells | 0 | 0 | 0 | 2 | 3 | 1 | Sinusoid congestion | 0 | 0 | 0 | 2 | 3 | 1 | Hemozoin deposition | 0 | 0 | 0 | 2 | 3 | 1 | Portal tract inflammation | 0 | 0 | 0 | 3 | 3 | 2 | Bile duct proliferation | 0 | 0 | 0 | 2 | 3 | 2 | Total histological score | 1/18 | 1/18 | 0/18 | 11/18 | 15/18 | 7/18 |
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