Effects of Early Transplantation of the Faecal Microbiota from Tibetan Pigs on the Gut Development of DSS-Challenged Piglets

Table 5

Effects of DSS challenge and FMT on the serum DOA activity and LPS concentration and on the mRNA expression levels of intestinal barrier-related genes in the intestines of piglets.

	DSS-		DSS+		SEM	value
	Micro-	Micro+	Micro-	Micro+		Micro	DSS
Jejunum
Occludin	1.000	0.946	0.945	0.859	0.034	0.327	0.319	0.826
ZO-1	1.000	1.024	0.992	0.933	0.035	0.819	0.508	0.580
MUC1	1.000^ab	1.186^a	0.316^b	0.364^b	0.088	0.159	<0.001	0.397
MUC2	1.000	1.010	0.545	0.570	0.083	0.908	0.007	0.962
RegIIIγ	1.000	1.167	0.804	0.974	0.067	0.215	0.155	0.991
Ileum
Occludin	1.000	0.965	0.929	0.867	0.055	0.680	0.475	0.906
ZO-1	1.000	1.011	0.910	0.962	0.042	0.728	0.441	0.819
MUC1	1.000	1.119	1.119	0.898	0.049	0.723	0.176	0.402
MUC2	1.000	0.980	0.962	1.049	0.059	0.794	0.903	0.677
RegIIIγ	1.000	1.023	0.940	0.919	0.053	0.992	0.468	0.845
Colon
Occludin	1.000^a	0.890^a	0.623^b	0.609^b	0.047	0.364	<0.001	0.484
ZO-1	1.000	0.915	0.747	0.766	0.064	0.803	0.137	0.690
MUC1	1.000	1.060	0.844	1.025	0.044	0.180	0.285	0.495
MUC2	1.000^ab	1.244^a	0.717^b	0.801^b	0.114	0.165	0.005	0.490
RegIIIγ	1.000^a	1.030^a	0.265^c	0.555^b	0.074	0.035	<0.001	0.082
IL-1β	1.000^b	0.839^b	1.631^a	1.182^b	0.074	0.003	<0.001	0.120
IL-10	1.000^c	1.531^ab	1.228^bc	1.739^a	0.080	0.001	0.074	0.931
Serum
DAO (U/L)	10.418	9.987	11.492	10.476	0.140	<0.001	<0.001	0.099
LPS (ng/mL)	68.155	67.322	70.929	69.472	1.208	0.654	0.340	0.903