Association of Polymorphisms of Metabolism-Related Genes with Psoriasis Vulgaris in Han Chinese

Table 3

Comparison of 18 SNPs between PsV cases and controls stratified for HLA-cw06 : 02(+) and HLA-cw06 : 02(-).

CHR	SNP	Gene	HLA-C06:02(+)							HLA-C06:02(-)
			MAF(+)				OR	95% CI		MAF(-)				OR	95% CI
			PsV	Con						PsV	Con
2	rs7593730	RBMS1	0.196	0.182	0.29	0.589	1.09	0.79-	1.50	0.171	0.185	0.58	0.445	0.91	0.72-	1.16
3	rs5186	AT1R	0.056	0.070	0.87	0.350	0.79	0.48-	1.30	0.058	0.060	0.03	0.861	0.97	0.66-	1.42
5	rs2303138	LNPEP	0.452	0.388	4.18	0.041	1.30	1.01-	1.67	0.448	0.414	2.22	0.136	1.15	0.96-	1.38
6	rs2247056	HLA	0.064	0.049	1.06	0.304	1.34	0.77-	2.34	0.099	0.126	3.25	0.072	0.76	0.57-	1.03
6	rs3177928	HLA	0.176	0.136	2.80	0.094	1.35	0.95-	1.92	0.075	0.044	8.83	0.003	1.75	1.21-	2.55
6	rs6931514	CDKAL1	0.493	0.515	0.52	0.472	0.91	0.71-	1.17	0.496	0.497	0.01	0.932	0.99	0.83-	1.19
6	rs805303	HLA	0.441	0.515	5.68	0.017	0.74	0.58-	0.95	0.332	0.423	16.23	5.62E-05	0.68	0.56-	0.82
10	rs4506565	TCF7L2	0.036	0.033	0.04	0.841	1.07	0.54-	2.12	0.039	0.044	0.28	0.600	0.88	0.56-	1.40
10	rs7901695	TCF7L2	0.036	0.030	0.22	0.641	1.18	0.58-	2.40	0.039	0.043	0.15	0.698	0.91	0.57-	1.45
12	rs11065987	BRAP	0.014	0.009	0.47	0.495	1.54	0.44-	5.35	0.009	0.008	0.14	0.710	1.21	0.45-	3.23
12	rs3184504	SH2B3	0.016	0.009	0.95	0.331	1.82	0.53-	6.23	0.009	0.009	0.00	0.988	1.01	0.39-	2.63
12	rs653178	ATXN2, SH2B3	0.017	0.009	0.98	0.323	1.84	0.54-	6.29	0.009	0.008	0.04	0.851	1.10	0.42-	2.90
16	rs255049	LCAT	0.147	0.146	0.01	0.939	1.01	0.72-	1.44	0.144	0.140	0.07	0.798	1.03	0.80-	1.34
17	rs4646994	ACE	0.259	0.266	0.05	0.816	0.97	0.72-	1.30	0.271	0.269	0.01	0.914	1.01	0.82-	1.26
19	rs1047781	FUT2	0.490	0.455	1.26	0.261	1.15	0.90-	1.48	0.490	0.444	3.85	0.050	1.20	1.00-	1.44
19	rs281379	FUT2	0.031	0.036	0.23	0.634	0.85	0.44-	1.66	0.027	0.014	4.50	0.034	1.95	1.04-	3.67
19	rs492602	FUT2	0.032	0.033	0.01	0.904	0.96	0.48-	1.91	0.027	0.013	5.05	0.025	2.04	1.08-	3.86
22	rs181362	UBE2L3	0.418	0.364	3.01	0.083	1.26	0.97-	1.62	0.437	0.434	0.02	0.889	1.01	0.84-	1.22