Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 Diabetes

Figure 1

Physiological function of nicotinamide N-methyltransferase (NNMT) and the related metabolic pathways. NA: nicotinamide; MNA: 1-methylnicotinamide; SAM: S-adenosyl-methionine; SAH: S-adenosyl-homocysteine; NAD⁺: nicotinamide adenine dinucleotide; ARTs: ADP-ribosyl transferases; PARPs: poly-ADP-polymerases.