Designing of Potential Polyvalent Vaccine Model for Respiratory Syncytial Virus by System Level Immunoinformatics Approaches

Figure 7

Schematic diagram of polyvalent vaccine construct. (a) 224-long peptide amino acid sequences consisting of an N-terminal adjuvant (black) directly linked to a multiepitope with the help of an EAAAK linker (red). With the help of AAY linkers, MHC I epitopes (purple) were linked, while HTL epitopes (green) were combined with the help of GPGPG linkers. (b) 3D model of the polyvalent construct. (c) Quality assessment of the model by Ramachandran plot indicates 69.4% residues were found in a favored region and 13.5% residues in the allowed region.

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