Morroniside Promotes PGC-1α-Mediated Cholesterol Efflux in Sodium Palmitate or High Glucose-Induced Mouse Renal Tubular Epithelial Cells

Figure 4

MOR attenuated cellular lipid and cholesterol accumulation in mRTECs stimulated by sodium palmitate (PA) or high glucose (HG). (a, c) Oil Red O staining reflected the lipid content of the mRTECs after 36 hours of PA or HG treatment ( μm). (b, d) Filipin cholesterol staining reflected cholesterol content of the mRTECs after 36 hours of PA or HG treatment ( μm). (e) Colorimetric analysis of total cholesterol (TC) and total triglyceride (TG) levels in mRTECs stimulated with PA for 36 hours. Data represent the (). , , and compared with the PA group. (f) Colorimetric analysis of TC and TG levels in mRTECs stimulated with HG for 36 hours. Data represent the (). , , and compared with the HG group.

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