Research Article

Morroniside Promotes PGC-1α-Mediated Cholesterol Efflux in Sodium Palmitate or High Glucose-Induced Mouse Renal Tubular Epithelial Cells

Figure 8

Schematic model of the PGC-1α/LXR pathways in mRTECs and the protective effect of MOR on PA or HG-induced lipid accumulation in mRTECs. MOR can activate the activities of ABCA1, ABCG1, and ApoE with PGC-1α as the central target to inhibit lipid accumulation in mRTECs.