Research Article
Development and Validation of a UPLC-MS/MS Method for the Quantitative Determination and Pharmacokinetic Analysis of Cirsimarin in Rat Plasma
Table 1
Accuracy, precision, matrix effect, and recovery of cirsimarin in rat plasma (n =6).
| | Concentration (ng/mL) | Accuracy (%) | Precision (RSD %) | Matrix effect (%) | Recovery (%) | | Intraday | Interday | Intraday | Interday |
| | 1 | 92.5 | 107.3 | 10.5 | 13.6 | 104.7 | 92.8 | | 4 | 101.8 | 99.4 | 3.4 | 6.9 | 106.6 | 84.2 | | 180 | 105.2 | 103.9 | 4.5 | 7.3 | 107.4 | 95.3 | | 2500 | 101.0 | 97.1 | 8.4 | 2.7 | 103.6 | 98.0 |
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