Trends of Antibacterial Resistance at the National Reference Laboratory in Cameroon: Comparison of the Situation between 2010 and 2017

Table 4

Some specific resistances of clinical interest as per WHO priority resistances and their relative change between 2010 and 2017, Centre Pasteur du Cameroun, Yaounde.

Categories	Resistance features	Overall		2010		2017		Relative change (%)	value
		Isolates	Feature frequency (%)	Isolates	Feature frequency (%)	Isolates	Feature frequency (%)
WHO priority 1	Imipenem-R^1Acinetobacter baumannii	167	15.6	65	6.2	102	21.6	+248.4	0.032
	Imipenem-R Pseudomonas aeruginosa	234	18.4	119	13.5	115	23.5	+74.1	< 0.01
	Imipenem-R Enterobacteriaceae	2,066	3.5	504	4.0	1,562	3.3	-17.5	< 10^-8
	3GC^2-R Enterobacteriaceae	3,643	32.1	1,818	23.8	1,825	40.4	+69.8	< 10^-15
WHO priority 2	Vancomycin-R Enterococcus spp	412	0.5	126	0.0	284	0.7	—	1
	Methicillin-R Staphylococcus aureus	412	34.2	262	27.3	150	46.0	+68.6	< 10^-3
	Fluoroquinolone-R Campylobacter spp	19	52.6	12	41.7	7	71.4	+71.4	0.3
	Fluoroquinolone-R Salmonella spp	144	5.6	103	3.9	41	9.5	+142.9	0.03
	3GC-R Neisseria gonorrhoeae	123	1.6	18	0.0	105	1.9	—	1
	Quinolone-R Neisseria gonorrhoeae	18	16.7	18	16.7	0	—	—	—
	Fluoroquinolone-R Neisseria gonorrhoeae	105	80.9	0	—	105	80.9	—	—
WHO priority 3	Penicillin nonsusceptible S^3. pneumoniae	84	5.9	56	5.2	28	7.6	+47.0	0.09
	Ampicillin-R Haemophilus influenzae	62	70.9	9	55.6	53	73.6	+32.4	< 0.01
	Fluoroquinolone-R Shigella spp	128	0.8	53	0.0	75	2.7	—	1
Other specific resistances	Fluoroquinolone-R Enterobacteriaceae	3,447	45.1	1710	34.0	1737	56.0	+65.8	< 10^-15
	3GC-R Escherichia coli	1,720	25.9	880	17.1	840	35.2	+105.8	< 10^-15
	Fluoroquinolone-R Escherichia coli	1,693	49.9	867	37.4	826	61.6	+64.5	< 10^-15
	Fluoroquinolone-R Mycoplasmas	3,505	63.8	1,636	62.8	1,869	64.6	+1.8	< 10^-3
	Fluoroquinolone-I/R^4 Mycoplasmas	3,505	97.6	1,636	98.6	1,869	96.8	-1.8	< 10^-3
	Cyclin-R Mycoplasmas	3,505	27.2	1,636	32.7	1,869	22.3	-31.8	< 10^-13
	Josamycin-R Mycoplasmas	3,505	1.10	1,636	1.1	1,869	1.2	+0.1	0.90