Research Article
Levels of C-Reactive Protein and Sodium May Differentiate a Perforated Appendix from a Nonperforated Appendix in Children
Table 1
Clinical, laboratory, and procedural parameters regarding acute appendicitis versus a perforated appendix.
| | Acute appendicitis | | Perforated appendicitis | | |
| | Number | 237 | | 69 | | | | Female : male () | 110 : 127 | | 22 : 47 | | | | Female (%) | 46 | | 32 | | | | Age (years) | 10 (7–12) | 237 | 6 (4–10) | 69 | <0.001† | | Temperature (°C) | 37.4 (37.0–38.0) | 188 | 38.2 (37.6–38.9) | 59 | <0.001† | | Tzanakis score | 10 (6–12) | 237 | 12 (9–15) | 69 | <0.001† | | Laboratory data | | | | | | | CRP (mg/dL) | 1.0 (0.2–3.3) | 236 | 10.8 (5.7–18.7) | 69 | <0.001† | | CLR (mg/dL/109/L) | 0.6 (0.2–2.5) | 111 | 10,3 (4.3–14.1) | 33 | <0.001† | | Lymphocytes (109/L) | | 112 | | 33 | 0.26‡ | | WBC (109/L) | | 237 | | 68 | <0.001‡ | | Sodium (mmol/L) | 140.0 (138.0–142.0) | 120 | 135.5 (133.0–138.3) | 54 | <0.001† | | Procedural data | | | | | | | DoHS (days) | 4 (3–4) | 237 | 7 (5–9) | 69 | <0.001† | | Procedure duration (min) | 50 (40–65) | 237 | 80 (60–104) | 69 | <0.001† | | Mode of surgery | | | | | | | Laparoscopy/conversion/open () | 234/1/2 | | 54/12/3 | | |
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CRP: C-reactive protein; WBC: white blood cell. CLR: C-reactive protein-to-lymphocyte ratio; DoHS: Duration of hospital stay. †Mann–Whitney -test; ‡two-sample -test. |
