hsa_circ_0023305 Enhances Laryngeal Squamous Cell Carcinoma Progression and Modulates TRPM7 via miR-218-5p Sponging

Figure 3

Downregulation of hsa_circ_0023305 decreases LSCC cell invasion in both in vitro and in vivo experiments. (a–d) Cell migration and invasion were analyzed in both Hep-2 and AMC-HN-8 cells using Transwell assays. Data are presented as the ; vs. sh-NC.(e, f) Live imaging showing the effects of circ-TRPS1 on metastasis of AMC-HN-8 cells 30 d after intravenous tail injection. The relative fluorescence density was calculated. Data are presented as the ; . (g, h) The numbers of metastatic foci in lung tissues were calculated according to the HE staining. The data are expressed as the . vs. sh-NC.

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