The Antioxidant Resveratrol Protects against Chondrocyte Apoptosis by Regulating the COX-2/NF-<i>κ</i>B Pathway in Created Temporomandibular Osteoarthritis

<div>Effect of COX-2 on IL-1<i>β</i>-induced chondrocyte degradation. Chondrocytes treated with COX-2 siRNA or control vehicle siRNA were subjected to IL-1<i>β</i>. Whole-cell lysis was subjected to western blot analysis. (a) The effects of COX-2 on inflammation pathway. Inhibition of COX-2 could decrease the expression of P65 and MMP13. (b) The effects of COX-2 on MCC degradation. Inhibition of COX-2 could increase the expression of SOX9 and COL2.</div>

BioMed Research International

fig1

Figure 1

Figure 1: The Antioxidant Resveratrol Protects against Chondrocyte Apoptosis by Regulating the COX-2/NF-<i>κ</i>B Pathway in Created Temporomandibular Osteoarthritis 

Figure 1 | The Antioxidant Resveratrol Protects against Chondrocyte Apoptosis by Regulating the COX-2/NF-κB Pathway in Created Temporomandibular Osteoarthritis 