The Antioxidant Resveratrol Protects against Chondrocyte Apoptosis by Regulating the COX-2/NF-<i>κ</i>B Pathway in Created Temporomandibular Osteoarthritis

<div>RES influenced the expression of COX-2/P65/MMPs and cartilage markers in mouse TMJOA model. (a) The mRNA expression of COX-2, P65, and MMP1 and MMP13 in MCC was detected by RT-PCR. RES treatment could suppress COX-2 expression and related inflammation pathway. (b) The levels of ACAN and COL2 gene expressions in the mouse condylar cartilage were determined by RT-PCR. 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BioMed Research International

fig4

Figure 4

Figure 4: The Antioxidant Resveratrol Protects against Chondrocyte Apoptosis by Regulating the COX-2/NF-<i>κ</i>B Pathway in Created Temporomandibular Osteoarthritis 

Figure 4 | The Antioxidant Resveratrol Protects against Chondrocyte Apoptosis by Regulating the COX-2/NF-κB Pathway in Created Temporomandibular Osteoarthritis 