Antidepressant Active Components of Bupleurum chinense DC-Paeonia lactiflora Pall Herb Pair: Pharmacological Mechanisms

Figure 4

Active compounds in Chaihu-Baishao promote hippocampal neurogenesis and regulate BDNF levels. BDNF: brain-derived neurotrophic factor; AKT: serine/threonine protein kinase; TrKB: tyrosine kinase B; CREB: cAMP response element-binding protein.