Review Article
Antidepressant Active Components of Bupleurum chinense DC-Paeonia lactiflora Pall Herb Pair: Pharmacological Mechanisms
Table 1
Active compounds in Bupleurum chinense DC-Paeonia lactiflora Pall herb pair inhibit inflammation and relieve oxidative stress.
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Notes: OFT: open field test; TST: tail suspension test; FST: forced swimming test; SPT: sucrose preference test; TLR4: Toll-like receptor 4; NF-κB: nuclear transcription factor-κB; HMGB1: High mobility group box 1; FGF2: fibroblast growth factor 2; LOOH: lipid hydroperoxides; SOD: Superoxide dismutase; MDA: malondialdehyde; CAT: catalase; GST: Glutathione S-transferase; AKT: serine/threonine protein kinase; IL-6: interleukin-6; TNF-α: Tumor necrosis factor-α; NLRP3: nucleotide-binding oligomerization domain-like receptor protein 3; CASP-11: Caspase-11; CASP-1: Caspase-1; GSDMD: Gasdermin D; IL-1β: interleukin-1β; TLR4: Toll-like receptor 4; LPS: lipopolysaccharide; CUMS: chronic unpredictable mild stress; OB: olfactory bulbectomy; CSDS: Chronic social stress defeat; CORT: cortisol; BCCAO: brain ischemia-reperfusion; ATP: adenosine triphosphate; IFN-α: Interferon-α; SLE: Systemic lupus erythematosus. |