Research Article

Zerumbone-Loaded Nanostructured Lipid Carrier Gel Enhances Wound Healing in Diabetic Rats

Table 2

Histological changes in wound tissues of diabetic rats treated with NLCG, SSDC, and ZER-NLCG.

ParameterLesion score (%)
Normal controlDiabetic controlNLCGSSDCZER-NLCG

Epidermal wound closure
Epithelial proliferation and differentiation
Epithelial ballooning
Keratin proliferation00
Edema00
Epidermal PMN cell infiltration
Dermal PMN cell infiltration
Neovascularization
Fibroblast proliferation
Collagen proliferation index

Values are . a,b,cMeans within row with different superscripts are significantly different at . PMN = polymorphonuclear cell.