Research Article
Zerumbone-Loaded Nanostructured Lipid Carrier Gel Enhances Wound Healing in Diabetic Rats
Table 2
Histological changes in wound tissues of diabetic rats treated with NLCG, SSDC, and ZER-NLCG.
| Parameter | Lesion score (%) | Normal control | Diabetic control | NLCG | SSDC | ZER-NLCG |
| Epidermal wound closure | | | | | | Epithelial proliferation and differentiation | | | | | | Epithelial ballooning | | | | | | Keratin proliferation | | 0 | 0 | | | Edema | | | | 0 | 0 | Epidermal PMN cell infiltration | | | | | | Dermal PMN cell infiltration | | | | | | Neovascularization | | | | | | Fibroblast proliferation | | | | | | Collagen proliferation index | | | | | |
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Values are . a,b,cMeans within row with different superscripts are significantly different at . PMN = polymorphonuclear cell. |