Research Article
Exploration of the Potential Mechanism of the Common Differentially Expressed Genes in Psoriasis and Atopic Dermatitis
Table 2
The top 20 hub genes in the protein-protein interaction network of 234 overlapped DEGs.
| Name | Degree | Betweenness centrality | Closeness centrality | Clustering coefficient | Stress | Average shortest path length |
| CXCL8 | 46 | 0.133 | 0.482 | 0.204 | 25680 | 2.073 | STAT1 | 42 | 0.085 | 0.449 | 0.353 | 17904 | 2.225 | PTPRC | 40 | 0.116 | 0.467 | 0.259 | 21216 | 2.14 | MMP9 | 36 | 0.131 | 0.466 | 0.195 | 26978 | 2.146 | CCL2 | 35 | 0.098 | 0.452 | 0.291 | 19580 | 2.213 | CCL5 | 35 | 0.027 | 0.421 | 0.343 | 8636 | 2.376 | MKI67 | 30 | 0.067 | 0.392 | 0.671 | 13962 | 2.551 | CCNB1 | 29 | 0.029 | 0.389 | 0.727 | 8476 | 2.567 | CCR7 | 28 | 0.016 | 0.411 | 0.378 | 5186 | 2.433 | CDC20 | 28 | 0.014 | 0.35 | 0.757 | 2808 | 2.854 | CDK1 | 28 | 0.018 | 0.361 | 0.757 | 3928 | 2.77 | KIAA0101 | 27 | 0.031 | 0.391 | 0.783 | 8688 | 2.556 | CXCL1 | 27 | 0.018 | 0.416 | 0.362 | 4458 | 2.404 | MX1 | 27 | 0.011 | 0.394 | 0.624 | 4112 | 2.539 | IRF1 | 26 | 0.011 | 0.389 | 0.572 | 3632 | 2.573 | IRF7 | 26 | 0.008 | 0.386 | 0.625 | 3208 | 2.59 | TPX2 | 26 | 0.001 | 0.325 | 0.871 | 330 | 3.073 | DLGAP5 | 26 | 0.002 | 0.333 | 0.88 | 1026 | 3 | AURKA | 26 | 0.002 | 0.333 | 0.88 | 1026 | 3 | CCNB2 | 26 | 0.005 | 0.341 | 0.874 | 1674 | 2.933 |
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