Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53

<div>Heat map showing differentially expressed genes (DEGs) and genes enriched in the KEGG pathway. (a) A bidirectional hierarchical clustering heat map was constructed. Expression values are log-fold changes (&gt;2 or &lt;-2, with a false discovery rate of &lt;0.05) between the corresponding oxaliplatin-resistant and the parental HT29 cells. (b) Significantly expressed genes in the glycerolipid metabolism pathway in oxaliplatin-resistant HT29 cells compared to parental HT29 cells. Black indicates no change in expression, green indicates downregulation, and red indicates upregulation, respectively.</div>

BioMed Research International

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Figure 2

Figure 2: Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53 

Figure 2 | Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53 