Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53

Table 3

Interaction of significant genes with drugs by the drug-gene interaction database.

Drug name	Prunetin	Guanidine	Disulfiram	Lidorestat	Zenarestat	Zopolrestat	Tolrestat	Fidarestat	Sorbinil	Sulindac	Exisulind
AKR1B1				IS:8.74	IS:4.37	IS:3.28	IS:2.91	IS:3.28	IS:2.19	IS:*0.79	IS:0.49
AKR1B10								IS:7.65		IS:0.7	IS: 1.7
ALDH2	IS:12.24	IS:7.65	IS:0.94
MGLL

FDA-approved drug clinically available. IS: interaction score.