The Effect of Osteoprotectin (OPG)/Receptor Activator of Nuclear Factor-<i>κ</i>B Ligand (RANKL)/Receptor Activator of Nuclear Factor-<i>κ</i>B (RANK) Gene Methylation on Aortic Valve Calcified

<div>Immunohistochemical staining and ELISA. (a) OPG immunohistochemical staining showed no positive staining in the noncalcified group and positive staining in the calcified group. (b) RANKL immunohistochemical staining showed no positive staining in the noncalcified group and positive staining in the calcified group. (c–d) ELISA showed significant differences in OPG and sRANKL levels between the two groups. 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BioMed Research International

fig4

Figure 4

Figure 4: The Effect of Osteoprotectin (OPG)/Receptor Activator of Nuclear Factor-<i>κ</i>B Ligand (RANKL)/Receptor Activator of Nuclear Factor-<i>κ</i>B (RANK) Gene Methylation on Aortic Valve Calcified 

Figure 4 | The Effect of Osteoprotectin (OPG)/Receptor Activator of Nuclear Factor-κB Ligand (RANKL)/Receptor Activator of Nuclear Factor-κB (RANK) Gene Methylation on Aortic Valve Calcified 