Bioinformatics Approach Predicts Candidate Targets for SARS-CoV-2 Infections to COPD Patients

Table 1

The GO pathways and their corresponding value and description for common DEGs.

GO	ID	Description	Gene ID	value
BP	GO:0009615	Response to virus	DMBT1/GBP1/LCN2/CCL8/RSAD2	1.84E-04
	GO:0071347	Cellular response to interleukin-1	GBP1/LCN2/CCL8/CCL18	2.10E-04
	GO:0010821	Regulation of mitochondrion organization	LMNA/BAP1/MOAP1/UBE2J2	2.24E-04
	GO:0001666	Response to hypoxia	ALDH3A1/LMNA/PGF/PKLR/TGFBR2	2.88E-04
	GO:1903533	Regulation of protein targeting	KCNE1/BAP1/UBE2J2	3.24E-04
	GO:0036293	Response to decreased oxygen levels	ALDH3A1/LMNA/PGF/PKLR/TGFBR2	3.31E-04
	GO:0070555	Response to interleukin-1	GBP1/LCN2/CCL8/CCL18	3.65E-04
	GO:0070482	Response to oxygen levels	ALDH3A1/LMNA/PGF/PKLR/TGFBR2	4.41E-04
	GO:0035162	Embryonic hemopoiesis	GATA2/TGFBR2	5.49E-04
	GO:0060216	Definitive hemopoiesis	GATA2/MEIS1	4.98E-04
CC	GO:1904724	Tertiary granule lumen	CHIT1/TNFAIP6	3.82E-03
	GO:0035580	Specific granule lumen	CHIT1/LCN2	4.82E-03
	GO:0045121	Membrane raft	KCNE1/TGFBR2/TUBA1A	1.55E-02
	GO:0098857	Membrane microdomain	KCNE1/TGFBR2/TUBA1A	1.56E-02
	GO:0098589	Membrane region	KCNE1/TGFBR2/TUBA1A	1.72E-02
	GO:0005652	Nuclear lamina	LMNA	1.83E-02
	GO:0005885	Arp2/3 protein complex	ARPC1B	1.83E-02
	GO:0042589	Zymogen granule membrane	DMBT1	1.83E-02
	GO:0030018	Z disc	KCNE1/NEBL	2.05E-02
	GO:0031588	Nucleotide-activated protein kinase complex	PRKAB1	2.32E-02
MF	GO:0008009	Chemokine activity	CCL8/CCL18	3.32E-03
	GO:0005539	Glycosaminoglycan binding	PGF/CCL8/TGFBR2/TNFAIP6	6.53E-04
	GO:0005200	Structural constituent of cytoskeleton	TUBA1A/ARPC1B/TUBA1C	7.43E-04
	GO:0048020	CCR chemokine receptor binding	CCL8/CCL18	2.56E-03
	GO:0005126	Cytokine receptor binding	PGF/CCL8/CCL18/TGFBR2	1.49E-03
	GO:0003924	GTPase activity	GBP1/RRAD/TUBA1A/TUBA1C	2.35E-03
	GO:0005525	GTP binding	GBP1/RRAD/TUBA1A/TUBA1C	3.93E-03
	GO:0032550	Purine ribonucleoside binding	GBP1/RRAD/TUBA1A/TUBA1C	4.09E-03
	GO:0001883	Purine nucleoside binding	GBP1/RRAD/TUBA1A/TUBA1C	4.20E-03
	GO:0032549	Ribonucleoside binding	GBP1/RRAD/TUBA1A/TUBA1C	4.24E-03