Rab22a Promotes Epithelial-Mesenchymal Transition in Papillary Thyroid Carcinoma by Activating PI3K/AKT/mTOR Signaling Pathway

Table 1

Association between Rab22a expression and clinical parameters in 101 patients with thyroid disease.

Clinicopathological characteristics	Rab22a positive	Rab22a negative	Total
Age (Y)
≤55	42	11	53	0.280
>55	12	6	18
Gender
Male	15	6	21	0.554
Female	39	11	50
Tumor size
≤2 cm	35	13	48	0.553
>2 cm	19	4	23
Lymphatic metastasis
Negative	23	8	31	0.746
Positive	31	9	40
TNM stage
I	45	14	59	0.925
II-IV	9	3	12
BRAF
Wild-type	27	8	35	0.854
V600E	19	5	24
Histological type
Papillary thyroid carcinoma	24	7	31	<0.001
Follicular carcinoma	24	9	33	<0.001
Thyroid medullary carcinoma	6	1	7	<0.001
Nodular goiter	0	30	30

P <0.05 (Fisher’s test).