Research Article

[Retracted] Identification of Hub Genes for Early Diagnosis and Predicting Prognosis in Colon Adenocarcinoma

Table 2

KEGG and Reactome annotation of DEGs in COAD.

GOCategoryDescriptionCount%Log10()Log10()

hsa04110KEGG pathwayCell cycle163.67-9.05-6.08
hsa04964KEGG pathwayProximal tubule bicarbonate reclamation51.15-4.32-2.26
hsa04923KEGG pathwayRegulation of lipolysis in adipocytes61.38-3.38-1.5
hsa04960KEGG pathwayAldosterone-regulated sodium reabsorption51.15-3.3-1.48
hsa04978KEGG pathwayMineral absorption51.15-2.65-1.03
R-HSA-1640170Reactome gene setsCell cycle419.4-10.9-7.44
R-HSA-1475029Reactome gene setsReversible hydration of carbon dioxide51.15-5.87-3.47
R-HSA-382551Reactome gene setsTransport of small molecules296.65-4.18-2.14
R-HSA-69273Reactome gene setsCyclin A/B1/B2 associated events during G2/M transition51.15-4.13-2.11
R-HSA-6804756Reactome gene setsRegulation of TP53 activity through phosphorylation81.83-3.58-1.64
R-HSA-109582Reactome gene setsHaemostasis245.5-3.35-1.5
R-HSA-8979227Reactome gene setsTriglyceride metabolism51.15-3.3-1.48
R-HSA-418594Reactome gene setsG alpha (i) signalling events173.9-2.89-1.16
R-HSA-420029Reactome gene setsTight junction interactions40.92-2.76-1.09
R-HSA-200425Reactome gene setsCarnitine metabolism30.69-2.74-1.09
R-HSA-420092Reactome gene setsGlucagon-type ligand receptors40.92-2.55-0.95
R-HSA-211945Reactome gene setsPhase I—functionalization of compounds71.61-2.5-0.91
R-HSA-6785807Reactome gene setsInterleukin-4 and interleukin-13 signalling71.61-2.46-0.88
R-HSA-983189Reactome gene setsKinesins51.15-2.38-0.82
R-HSA-422085Reactome gene setsSynthesis, secretion, and deacylation of ghrelin30.69-2.34-0.8

Abbreviations: KEGG: Kyoto Encyclopedia of Genes and Genomes; DEGs: differentially expressed genes; COAD: colon adenocarcinoma.