Research Article

[Retracted] Radiosensitizing Effect of Celastrol by Inhibiting G2/M Phase Arrest Induced by the c-myc Gene of Human SW1353 Chondrosarcoma Cells: Network and Experimental Analyses

Table 3

Summary of celastrol information.

Drug nameTargetSymbol

TripterineNR3C1Glucocorticoid receptor
VEGFAVascular endothelial growth factor A

MOL003186CCND1G1/S-specific cyclin-D1
BCL2Apoptosis regulator Bcl-2
BCL2L1Bcl-2-like protein 1

BAXApoptosis regulator BAX
FLT1Vascular endothelial growth factor receptor 1
KDRVascular endothelial growth factor receptor 2
MMP9Matrix metalloproteinase-9
JUNTranscription factor AP-1
PTGS2Prostaglandin G/H synthase 2
BIRC5Baculoviral IAP repeat-containing protein 5
BIRC2Baculoviral IAP repeat-containing protein 2
CFLARCASP8 and FADD-like apoptosis regulator
AKR1B1Aldose reductase
CDC37Hsp90 cochaperone Cdc37
MMP272 kDa type IV collagenase
TIMP1Metalloproteinase inhibitor 1
TIMP2Metalloproteinase inhibitor 2
MMP1Interstitial collagenase
MYCMyc proto-oncogene protein
FNDC3BFibronectin
COL7A1Collagen alpha-1 (VII) chain
COL4A4Transforming growth factor beta-1
RELACollagen alpha-4 (IV) chain